JetBlue will be jetting off on its first official commercial flight to Cuba this week, becoming the first American airline to launch commercial flights to the Caribbean island nation in over five decades. The airline has already been sending planes on charter flights from New York since President Obama eased travel restrictions that had remained in place since the Cold War.

American Airlines also launched charter flights to Havana late last year, and several other airlines like Delta, Southwest, and Spirit have received tentative approval from the U.S. Department of Transportation to fly to Cuba, albeit with as yet unconfirmed schedules. Because of this, the airlines are not permitted to sell Havana airfare until they have received final government approval.

Jus twenty non-stop flights will be allowed to fly out of the United States to Havana, fourteen of those from major Florida cities like Tampa, Miami, Fort Lauderdale, and Orlando. The remaining six flights will connect the capital city of Cuba with the following cities: Houston, Charlotte, Atlanta, Newark, Los Angeles, and New York.

Six different airlines will launch weekly flights to other cities in Cuba during the next few months, collectively making for more than 150 weekly flights. If you’re interested in visiting Cuba, there are several entry requirements that must be fulfilled prior to your trip, which you can read more about through the U.S. embassy in Havana website.

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